Cefixime
Uses: uncomplicated gonorrhoea.
Contraindications: hypersensitivity to cefalosporins.
Precautions: sensitivity to Beta Lactam antibacterials (avoid if history of immediate hypersensitivity reaction; see introductory note above); moderate renal impairment; pregnancy and breastfeeding; use may result in false positive urinary glucose (if tested for reducing substances) and false positive Coombs' test;
Dose:
Uncomplicated anogenital gonorrhoea, by mouth, ADULT, 400 mg as a singl dose.
Adverse effects: diarrhoea, nausea and vomiting, abdominal discomfort, headache; rarely antibiotic-associated colitis (particularly with higher doses); allergic reactions including rash, pruritus, urticaria, serum sickness-like reactions, fever and arthralgia, and anaphylaxis; erythema multiforme and toxic epidermal necrolysis reported; transient hepatitis, cholestatic jaundice; eosinophilia and blood disorders (including thrombocytopenia, leucopenia, agranulocytosis, aplastic anaemia, and haemolytic anaemia); reversible
6. Anti-infective medicines
interstitial nephritis, hyperactivity, nervousness, sleep disturbances, hallucinations, confusion, hypertonia, and dizziness.
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